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Around one in 200 people have a mutation that strongly increases body mass index and/or risk of type 2 diabetes.

One in 400 people have a mutation that strongly increases risk of obesity. The subjective experience of having a mutation like this is poorly documented.

Large-scale genome sequencing studies are showing that nearly everyone has a set of rare, high-impact genetic variants that influence a range of noticeable traits, ranging from blood measurements to body composition to behavior.